Spirochete & Bacteria Silver Stain
The Warthin-Starry silver stain is a specialized technique for demonstrating difficult-to-visualize microorganisms including spirochetes (Treponema pallidum, Borrelia), bacteria (Helicobacter pylori, Bartonella), and other small organisms. This method deposits silver onto bacterial cell walls and flagella, rendering them visible as black or brown-black structures against a pale yellow-green background. The Warthin-Starry stain is the gold standard for detecting H. pylori in gastric biopsies, identifying spirochetes in syphilis and Lyme disease, and demonstrating Donovan bodies in granuloma inguinale. The technique requires careful attention to incubation times for optimal results.
Small curved rods appear black in gastric mucosa. Found on epithelial surface and in gastric pits. Confirm with Giemsa if needed.
Thin spiral organisms (6-20ฮผm) stain black. Treponema pallidum in syphilis, Borrelia in Lyme disease visible.
Pleomorphic bacilli in cat scratch disease and bacillary angiomatosis. Cluster in vascular proliferations.
Essential for gastric pathology (H. pylori), dermatopathology (spirochetes), and infectious disease diagnosis.
Contact our team for specifications, protocols, and availability.